Thermo Fisher Scientific CDC14B/CDC14C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CDC14B(Accession O60729), corresponding to amino acid residues A14-R64. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDC14B/CDC14C,uniProtId:A4D256-1,ncbiNodeId:9606,antigenRange:1,antigenLength:447,antigenImageFileName:PA5-99828_CDC14BCDC14C_A4D256-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99828_CDC14BCDC14C_A4D256-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:CDC14B/CDC14C,uniProtId:O60729-1,ncbiNodeId:9606,antigenRange:14-64,antigenLength:498,antigenImageFileName:PA5-99828_CDC14BCDC14C_O60729-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99828_CDC14BCDC14C_O60729-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818761

Product Specific Information

Antibody detects endogenous levels of total CDC14B/C.

Target Information

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.