Thermo Fisher Scientific MCM8 Polyclonal Antibody
MCM8 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human 및 Rat 시료에 반응. Western Blot과 Immunocytochemistry에 사용 가능. 액상 형태, 1 mg/mL 농도, PBS 버퍼 및 50% 글리세롤 포함. 연구용으로만 사용.
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- PA599829
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCM8 (Accession Q9UJA3), corresponding to amino acid residues K734–N784 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818762 |
Product Specific Information
Antibody detects endogenous levels of total MCM8.
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in replication fork formation and recruitment of other DNA replication-related proteins. MCM8 contains a conserved central domain and co-immunoprecipitates with MCM4, 6, and 7, suggesting interaction with other MCM proteins and a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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