Thermo Fisher Scientific GABA(A) R beta-3 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABA(A) receptor beta-3 subunit for WB and IHC applications. Recognizes human GABRB3 with high specificity. Lyophilized form, unconjugated, stored at -20°C for long-term stability. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous (PubMed)
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 300–400 of human GABA(A) receptor subunit beta-3 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C and avoid freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: GABRB3.
Target Information
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the central nervous system. It is formed by decarboxylation of glutamate and acts through two receptor types: GABA-A and GABA-B.
Binding of GABA to GABA-A receptors increases chloride ion transport into neurons, leading to signal inhibition.
Deficiency in GABA-mediated signaling can cause uncontrolled neuronal activity, resulting in blackouts, rapid body contractions, seizures, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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