Thermo Fisher Scientific SPP Polyclonal Antibody
Thermo Fisher Scientific의 SPP Polyclonal Antibody는 Human 시료에 반응하며 Rabbit에서 유래한 IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 327 to 377 of Human Signal Peptide Peptidase Like 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm.
Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides.
May play a role in graft rejection.
May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein.
Involved in the intramembrane cleavage of the integral membrane protein PSEN1.
Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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