Thermo Fisher Scientific SPP Polyclonal Antibody
Rabbit 유래의 Polyclonal 항체로 Signal Peptide Peptidase Like 1 단백질(인간 HM13)을 인식합니다. Western blot 및 Immunoprecipitation에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 327 to 377 of Human Signal Peptide Peptidase Like 1 (HM13, UniProt ID: Q8TCT9-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Catalyzes intramembrane proteolysis of certain signal peptides after cleavage from preproteins, releasing fragments from the ER membrane into the cytoplasm. Required for generation of lymphocyte surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection and in removal of signal peptides attached to hepatitis C virus core protein after initial processing. Involved in intramembrane cleavage of PSEN1 and XBP1 isoform 1 in a DERL1/RNF139-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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