Thermo Fisher Scientific CRSP9 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
KREEKLEDLK LLFVHVHHLI NEYRPHQARE TLRVMMEVQK RQRLETAERF QKHLERVIEM I

Target Information

The activation of gene transcription is a multistep process triggered by factors that recognize transcriptional enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by the RNA polymerase II complex. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. It is also a component of other multisubunit complexes, such as thyroid hormone receptor-associated proteins, which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.