
Thermo Fisher Scientific ENG Monoclonal Antibody (OTI8B8), TrueMAB
인간 ENG 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. CD105(Endoglin) 연구용으로 사용되며, 동결건조 형태로 제공됩니다. PBS 완충액에 8% 트레할로스를 포함하고, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B8 |
| Immunogen | Full length human recombinant protein of human ENG produced in HEK293T cells (CD105 / Endoglin, UniProt ID: P17813-1, amino acids 1–658) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, indicating it as a proliferation-associated endothelial marker. CD105 binds TGF-β1 and TGF-β3 with high affinity, but not TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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