Thermo Fisher Scientific ENG Monoclonal Antibody (OTI8B8), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:1,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, indicating it as a proliferation-associated endothelial marker. CD105 binds TGF-β1 and TGF-β3 with high affinity, but not TGF-β2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.