Thermo Fisher Scientific Procollagen Type I C-Peptide (PIP) Monoclonal Antibody (PC8-7)

Applications

Tested Dilution

Publications

Western Blot (WB)

10 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

10 µg/mL

-

ELISA (ELISA)

0.2 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Dog, Horse, Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

PC8-7

Immunogen

Human Procollagen Type I C-Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5-1.0 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 1% BSA

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 50 µL of distilled water (final concentration 2 mg/mL).

Target Information

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum depends on age and sex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.