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Thermo Fisher Scientific MA2 Polyclonal Antibody
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Thermo Fisher Scientific MA2 Polyclonal Antibody

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Thermo Fisher Scientific의 MA2 Polyclonal Antibody는 인간 PNMA2 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤이 포함되어 안정적으로 보관 가능합니다.

카탈로그번호
PA581995
판매단위
pk
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마지막 업데이트 2025. 08. 01. 오후 01:54
Thermo Fisher Scientific PA581995 MA2 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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761,500원VAT 포함 837,650원

Thermo Fisher Scientific · Thermo Fisher Scientific MA2 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 1:200–1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human PNMA2. Recombinant protein control fragment (Product # RP-102104)
Conjugate Unconjugated
Form Liquid
Concentration 0.30 mg/mL
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions Wet ice
RRID AB_2789156

Product Specific Information

Immunogen sequence:

KQENANAVLL ELLEDTDVSA IPSEVQGKGG VWKVIFKTPN QDTEFLERLN LFLEKEGQTV SGMFRALGQE GVSPATVPCI SPELLAHLLG QAMAHAPQPL LPMRYRKLRV FSGSAVPAPE EESFEVWLEQ ATEIVKEWPV TEAEKKRWL

Target Information

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a paraneoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by the presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum.

These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a “brain-testis-cancer” gene related to other paraneoplastic syndromes and tumors.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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