Thermo Fisher Scientific MA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PNMA2. Recombinant protein control fragment (Product #RP-102104). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MA2,uniProtId:Q9UL42-1,ncbiNodeId:9606,antigenRange:58-206,antigenLength:364,antigenImageFileName:PA5-81995_MA2_Q9UL42-1_Rabbit.svg,antigenImageFileNamePDP:PA5-81995_MA2_Q9UL42-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.30 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789156

Product Specific Information

Immunogen sequence: KQENANAVLL ELLEDTDVSA IPSEVQGKGG VWKVIFKTPN QDTEFLERLN LFLEKEGQTV SGMFRALGQE GVSPATVPCI SPELLAHLLG QAMAHAPQPL LPMRYRKLRV FSGSAVPAPE EESFEVWLEQ ATEIVKEWPV TEAEKKRWL

Target Information

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a brain-testis-cancer gene related to other para-neoplastic syndromes and tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.