Thermo Fisher Scientific LEF1 Polyclonal Antibody
Thermo Fisher Scientific의 LEF1 Polyclonal Antibody는 인간 LEF1 단백질을 인식하는 토끼 유래 폴리클로날 항체로, WB, IHC(P), ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LEF1 (amino acids 176–309). Recombinant protein control fragment: Product #RP-100720 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789161 |
Product Specific Information
Immunogen sequence:
SDVNSKQGMS RHPPAPDIPT FYPLSPGGVG QITPPLGWQG QPVYPITGGF RQPYPSSLSV DTSMSRFSHH MIPGPPGPHT TGIPHPAIVT PQVKQEHPHT DSDLMHVKPQ HEQRKEQEPK RPHIKKPLNA FMLY
Target Information
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1.
The encoded protein binds to a functionally important site in the T-cell receptor-alpha enhancer, conferring maximal enhancer activity.
It is involved in the Wnt signaling pathway and may play a role in hair cell differentiation and follicle morphogenesis.
Mutations have been associated with somatic sebaceous tumors and other cancers, including androgen-independent prostate cancer.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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