Thermo Fisher Scientific HSP27 Polyclonal Antibody
Rabbit polyclonal antibody targeting HSP27 (HSPB1) for WB, ICC/IF, and IP applications. Recognizes recombinant human HSP27 protein. Supplied as liquid, unconjugated, 0.2 mg/mL concentration. Suitable for research use; provides reliable detection of str...
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 10–15 µg/mL |
| Immunoprecipitation (IP) | 5–10 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human Heat Shock Protein 27 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_794515 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
In response to adverse environmental changes, cells increase the expression of heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein functioning as a molecular chaperone that maintains denatured proteins in a folding-competent state. It contributes to stress resistance and actin organization. Through its chaperone activity, HSP27 regulates biological processes including phosphorylation and axonal transport of neurofilament proteins. Mutations in this gene can lead to Charcot-Marie-Tooth disease 2F and distal hereditary motor neuronopathy 2B.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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