Thermo Fisher Scientific MZB1 Polyclonal Antibody
Rabbit polyclonal antibody against human MZB1 (PERP1) for WB, IHC, ELISA, and IP applications. Recombinant immunogen-based, preservative-free formulation. High specificity and purity, ideal for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:10,000 | – |
| ELISA | 1:5,000–1:10,000 | – |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PERP1/MZB1 protein (Met 1–Thr 185) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788107 |
Product Specific Information
This product is preservative-free.
It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PERP1/MZB1.
Target Information
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. It may act as a molecular chaperone or oxidoreductase, displaying low oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis.
MZB1 helps to diversify peripheral B-cell functions by regulating Ca²⁺ stores, antibody secretion, and integrin activation. It also acts as a hormone-regulated adipokine/proinflammatory cytokine implicated in chronic inflammation, affecting cellular expansion and insulin response in adipocytes, and may play a role in the onset of insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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