Thermo Fisher Scientific MVP Polyclonal Antibody
인간 MVP 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, ICC/IF, IP에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로 약물 내성 관련 단백질 분석에 적합.
- 카탈로그번호
- PA580836
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:300–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1–4 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human MVP (major vault protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788105 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MVP (major vault protein).
Target Information
The MVP gene encodes the major vault protein, a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression of this protein is a potentially useful marker of clinical drug resistance.
This gene produces two transcripts using alternative exon 2 sequences; however, the open reading frames are identical in both transcripts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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