Thermo Fisher Scientific MMP1 Monoclonal Antibody (F15 P3 B6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

F15 P3 B6

Immunogen

Synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MMP1,uniProtId:P03956-1,ncbiNodeId:9606,antigenRange:366-376,antigenLength:469,antigenImageFileName:MA1-771_MMP1_P03956-1_House_mouse.svg,antigenImageFileNamePDP:MA1-771_MMP1_P03956-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_889472

Product Specific Information

MA1-771 contains 100 µg of in vitro produced, protein A purified antibody (1 mg/mL) in PBS containing 1 mg/mL BSA and 0.05% sodium azide.

MA1-771 detects MMP-1 from human samples.

MA1-771 has been successfully used in Western blot applications. By Western blot, MA1-771 detects a ~50 kDa band representing MMP-1 from A431 and K562 cell lysates.

The MA1-771 immunogen is a synthetic peptide corresponding to residues C(366) S S F G F P R T V K H(376) of human MMP-1.

Target Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP`s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.