Thermo Fisher Scientific SNX9 Monoclonal Antibody (OTI1E4), TrueMAB
SNX9 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1E4). Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. Human 및 Dog 반응성. Lyophilized 형태, PBS buffer에 trehalose 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E4 |
| Immunogen | Full length human recombinant protein of human SNX9 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The SNX9 gene encodes a member of the sorting nexin family, which contains a phox (PX) domain involved in intracellular trafficking.
Unlike some family members, SNX9 does not have a coiled-coil region but includes an SH3 domain near its N-terminus.
It interacts with cytoplasmic domains of precursor forms of ADAM9 and ADAM15, and binds the beta-appendage domain of adaptor protein 2 (AP-2), assisting AP-2 function at the plasma membrane.
SNX9 also interacts with activated Cdc42-associated kinase-2 to regulate degradation of epidermal growth factor receptor (EGFR) protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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