Thermo Fisher Scientific BSG Monoclonal Antibody (OTI4D3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 is a member of the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
Functions include facilitating cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, and roles in cell development, activation, fetal development, and retinal function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.