Thermo Fisher Scientific PCDH1 (Protocadherin 1) Monoclonal Antibody (CSTEM31), eBioscience

Applications and Tested Dilutions

Product Specifications

Available Formats

• Alexa Fluor 488
• PE
• Request custom conjugation

Product Specific Information

The monoclonal antibody CSTEM31 reacts with human Protocadherin-1 (PCDH1), also known as cadherin-like protein 1.
This antibody has been reported for use in immunocytochemical staining and flow cytometric analysis.
(Fluorochrome-conjugated CSTEM31 is recommended for use in flow cytometry.)

Applications Tested:

• Immunocytochemistry: ≤ 5 µg/mL on formaldehyde-fixed and permeabilized human iPSCs
• Flow Cytometry: ≤ 0.5 µg/test on human iPSCs
  A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL.
  Cell number should be determined empirically and can range from 10⁵ to 10⁸ cells/test.

Target Information

Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion.
It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y).
These proteins possess seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, and can exist in two isoforms (short and long).

Expression and Function:

• Expressed in various tissues and organs such as brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, and reproductive organs.
• Plays a role in early development and mature tissues.
• Identified as a susceptibility gene for Bronchial Hyperresponsiveness in humans.
• Expressed on human pluripotent stem cells (hPSCs).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.