Thermo Fisher Scientific Phospho-FLT3 (Tyr969) Monoclonal Antibody (T.602.6)
Human 및 Mouse 시료에 반응하는 FLT3 인산화형(Tyr969) 특이 단일클론 항체. Western blot에 1:1000 희석으로 검증됨. 액상 형태이며 Affinity chromatography로 정제됨. 세포 내 신호전달 및 백혈병 관련 연구용으로 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T.602.6 |
| Immunogen | Synthetic phosphopeptide corresponding to the sequence surrounding pTyr969 of human FLT3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 63 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10988512 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs via binding of the FLT3 ligand to its extracellular domain, inducing homodimer formation and receptor autophosphorylation. The activated receptor phosphorylates and activates multiple cytoplasmic effector molecules involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation mutations of FLT3 are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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