Thermo Fisher Scientific HACE1 Monoclonal Antibody (OTI4E10), TrueMAB
HACE1 단백질을 표적으로 하는 마우스 단클론 항체로 Western blot에 적합. 인간 시료 반응성, 1 mg/mL 농도, 액상 형태. PBS/BSA/glycerol 완충액에 보존되며 -20°C 보관 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific HACE1 Monoclonal Antibody (OTI4E10), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E10 |
| Immunogen | Full length human recombinant protein of human HACE1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, serving as a signal for Golgi reassembly after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and degradation of active RAC1, playing a role in host defense against pathogens. May also act as a transcription regulator via interaction with RARB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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