Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, and renal cancer tumors.
Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder characterized by dysplasia or degeneration of the kidney, retina, and cerebellum.
SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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