Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SDCCAG8 protein. Validated for ICC/IF applications with high specificity. Supplied unconjugated in liquid form, 1 mg/mL concentration. Suitable for research use only; store at 4°C short term or -20°C long term.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 19–257 of SDCCAG8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553281 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, and renal cancer tumors.
Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder characterized by dysplasia or degeneration of the kidney, retina, and cerebellum.
SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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