Thermo Fisher Scientific DVL1 Polyclonal Antibody
DVL1 단백질을 표적으로 하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 IHC에 적합하며, 인간 시료에 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (IHC) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Dishevelled-1 (Arg150–Leu215) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610458 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human DVL-2 and DVL-3 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
DVL1, the human homolog of the Drosophila dishevelled gene (dsh), encodes a cytoplasmic phosphoprotein that regulates cell proliferation and acts as a transducer molecule for developmental processes such as segmentation and neuroblast specification.
DVL1 is considered a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1, and their phenotypes may be consistent with defects expected from aberrant DVL gene expression during development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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