Thermo Fisher Scientific TECK Polyclonal Antibody
Human TECK(CCL25)에 특이적인 goat polyclonal antibody로, Western blot 및 neutralization assay에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 보존제가 없는 동결건조 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Neutralization (Neu) | 5–40 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human CCL25/TECK (Gln24–Leu150) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610344 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant mouse CCL25/TECK is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Chemokines play an important role in regulating the trafficking of developing T cells within the thymus.
Chemokine C-C thymus expressed chemokine (TECK), also designated as chemokine ligand 25 (CCL25), small inducible cytokine A25, or CK b-15, is expressed predominantly in thymic dendritic cells, thymic epithelial cells, and in the small intestine.
TECK, a CCR9 ligand, has suppressive activity against immature subsets of myeloid progenitors stimulated by multiple growth factors.
It delivers signals through CCR9, which is crucial for the navigation of developing thymocytes.
Bone marrow pre-pro-B cells and progenitors capable of generating pro-B colonies migrate to TECK, a response lost in later stages of B cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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