Thermo Fisher Scientific GLB1L3 Polyclonal Antibody

Thermo Fisher Scientific GLB1L3 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).

Target Information

GLB1L3 (beta-galactosidase-1-like protein 3) is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. It exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. Chromosome 11, with approximately 135 million base pairs and 1,400 genes, represents around 4% of human genomic DNA and is rich in gene–disease associations. Genes encoded on chromosome 11, such as Atm, are crucial for cell cycle regulation and apoptosis following DNA damage. Mutations in Atm lead to ataxia-telangiectasia, while other syndromes like Jervell and Lange-Nielsen, Jacobsen, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz are also associated with defects in chromosome 11.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.