Thermo Fisher Scientific MSC Polyclonal Antibody
MSC 단백질을 인식하는 폴리클로날 항체로 Western blot에 최적화됨. 인간 시료에 반응하며, 합성 펩타이드 면역원으로 제작됨. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PLKSDWNSLDGIIR) corresponding to the C-terminus amino acids of MSC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10982409 |
Product Specific Information
This antibody is predicted to react with human based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in promoter regions of many muscle-specific terminal differentiation genes.
MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to repress MyoD activity, resulting in delayed expression of muscle-specific genes.
Musculin is highly expressed in undifferentiated and proliferating myoblasts and is downregulated during myogenesis and at the onset of terminal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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