Thermo Fisher Scientific ORC6 Polyclonal Antibody
Human ORC6 단백질을 인식하는 Goat Polyclonal Antibody로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태입니다. 연구용으로 DNA 복제 및 세포분열 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (ENAASAQKATAE) corresponding to the C-terminus amino acids of ORC6L (aa 241–252) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10987490 |
Target Information
The origin recognition complex (ORC) is a highly conserved six-subunit protein complex essential for the initiation of DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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