Thermo Fisher Scientific RALBP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human RALBP1 protein. Suitable for immunocytochemistry (ICC/IF) applications. Affinity-purified and supplied in liquid form with PBS/glycerol buffer. For research use only, not for diagnostic purposes.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 57–188). Recombinant protein control fragment (Product #RP-109972). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092106 |
Product Specific Information
Immunogen sequence:
PPDVVSDDEK DHGKKKGKFK KKEKRTEGYA AFQEDSSGDE AESPSKMKRS KGIHVFKKPS FSKKKEKDFK IKEKPKEEKH KEEKHKEEKH KEKKSKDLTA ADVVKQWKEK KKKKKPIQEP EVPQIDVPNL KP
Antigen sequence identity:
- Mouse: 95%
- Rat: 95%
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), serving as a major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
This protein can catalyze transport of glutathione conjugates and xenobiotics, contributing to multidrug resistance. It also acts as a scaffold protein facilitating endocytotic complex formation during interphase and interacts with CDC2 to regulate endocytosis. One of its substrates is EPN1/Epsin.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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