Thermo Fisher Scientific RRAGC Polyclonal Antibody

Thermo Fisher Scientific RRAGC Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:3,000
Publications: -

Product Specifications

Product Specific Information

Keep as concentrated solution.
Predicted reactivity: Mouse (96%), Rat (96%), Sheep (100%), Bovine (98%).
Positive Control: 293T, A431, HeLa, NIH-3T3, Raw 264.7, C2C12.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form.
In its active form, RRAGC participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB — a crucial step in the activation of the TOR signaling cascade by amino acids.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.