Thermo Fisher Scientific TCP-1 beta Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 206-535 of human TCP1 beta/TCP1 beta/CCT2 (NP_0064221) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TCP-1 beta,uniProtId:P78371-1,ncbiNodeId:9606,antigenRange:206-535,antigenLength:535,antigenImageFileName:PA5-93047_TCP-1_beta_P78371-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93047_TCP-1_beta_P78371-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.26 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806601

Product Specific Information

Immunogen sequence: GGSLADSYLD EGFLLDKKIG VNQPKRIENA KILIANTGMD TDKIKIFGSR VRVDSTAKVA EIEHAEKEKM KEKVERILKH GINCFINRQL IYNYPEQLFG AAGVMAIEHA DFAGVERLAL VTGGEIASTF DHPELVKLGS CKLIEEVMIG EDKLIHFSGV ALGEACTIVL RGATQQILDE AERSLHDALC VLAQTVKDSR TVYGGGCSEM LMAHAVTQLA NRTPGKEAVA MESYAKALRM LPTIIADNAG YDSADLVAQL RAAHSEGNTT AGLDMREGTI GDMAILGITE SFQVKRQVLL SAAEAAEVIL RVDNIIKAAP RKRVPDHHPC; Positive Samples: MCF7, SKOV3, A-549, HT-29, Mouse spleen, Mouse ovary, Mouse heart; Cellular Location: Cytoplasm

Target Information

TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.