Thermo Fisher Scientific TMPRSS2 Monoclonal Antibody (2F4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2F4

Immunogen

TMPRSS2 (NP_005647, 383 a.a. approximately 492 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMPRSS2,uniProtId:O15393-1,ncbiNodeId:9606,antigenRange:383-492,antigenLength:492,antigenImageFileName:H00007113-M05_TMPRSS2_O15393-1_House_mouse.svg,antigenImageFileNamePDP:H00007113-M05_TMPRSS2_O15393-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GWGATEEKGK TSEVLNAAKV LLIETQRCNS RYVYDNLITP AMICAGFLQG NVDSCQGDSG GPLVTSKNNI WWLIGDTSWG SGCAKAYRPG VYGNVMVFTD WIYRQMRADG

Target Information

TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.