Thermo Fisher Scientific TMEM1 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TMEM1 (NP_003265.3, 1 a.a. approximately 1259 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRAPPC10,uniProtId:P48553-1,ncbiNodeId:9606,antigenRange:1-1259,antigenLength:1259,antigenImageFileName:H00007109-D01P_TRAPPC10_P48553-1_Rabbit.svg,antigenImageFileNamePDP:H00007109-D01P_TRAPPC10_P48553-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MDASEEPLPP VIYTMENKPI VTCAGDQNLF TSVYPTLSQQ LPREPMEWRR SYGRAPKMIH LESNFVQFKE ELLPKEGNKA LLTFPFLHIY WTECCDTEVY KATVKDDLTK WQNVLKAHSS VDWLIVIVEN DAKKKNKTNI LPRTSIVDKI RNDFCNKQSD RCVVLSDPLK DSSRTQESWN AFLTKLRTLL LMSFTKNLGK FEDDMRTLRE KRTEPGWSFC EYFMVQEELA FVFEMLQQFE DALVQYDELD ALFSQYVVNF GAGDGANWLT FFCQPVKSWN GLILRKPIDM EKRESIQRRE ATLLDLRSYL FSRQCTLLLF LQRPWEVAQR ALELLHNCVQ ELKLLEVSVP PGALDCWVFL SCLEVLQRIE GCCDRAQIDS NIAHTVGLWS YATEKLKSLG YLCGLVSEKG PNSEDLNRTV DLLAGLGAER PETANTAQSP YKKLKEALSS VEAFEKHYLD LSHATIEMYT SIGRIRSAKF VGKDLAEFYM RKKAPQKAEI YLQGALKNYL AEGWALPITH TRKQLAECQK HLGQIENYLQ TSSLLASDHH LTEEERKHFC QEILDFASQP SDSPGHKIVL PMHSFAQLRD LHFDPSNAVV HVGGVLCVEI TMYSQMPVPV HVEQIVVNVH FSIEKNSYRK TAEWLTKHKT SNGIINFPPE TAPFPVSQNS LPALELYEMF ERSPSDNSLN TTGIICRNVH MLLRRQESSS SLEMPSGVAL EEGAHVLRCS HVTLEPGANQ ITFRTQAKEP GTYTLRQLCA SVGSVWFVLP HIYPIVQYDV YSQEPQLHVE PLADSLLAGI PQRVKFTVTT GHYTIKNGDS LQLSNAEAML ILCQAESRAV VYSNTREQSS EAALRIQSSD KVTSISLPVA PAYHVIEFEL EVLSLPSAPA LGGESDMLGM AEPHRKHKDK QRTGRCMVTT DHKVSIDCPW SIYSTVIALT FSVPFRTTHS LLSSGTRKYV QVCVQNLSEL DFQLSDSYLV DTGDSTDLQL VPLNTQSQQP IYSKQSVFFV WELKWTEEPP PSLHCRFSVG FSPASEEQLS ISLKPYTYEF KVENFFTLYN VKAEIFPPSG MEYCRTGSLC SLEVLITRLS DLLEVDKDEA LTESDEHFST KLMYEVVDNS SNWAVCGKSC GVISMPVAAR ATHRVHMEVM PLFAGYLPLP DVRLFKYLPH HSAHSSQLDA DSWIENDSLS VDKHGDDQPD SSSLKSRGSV HSACSSEHKG LPMPRLQALP AGQVFNSSSG TQVLVIPSQD DHVLEVSVT

Target Information

TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.