Thermo Fisher Scientific p53AIP1 Polyclonal Antibody
Thermo Fisher Scientific의 p53AIP1 Polyclonal Antibody는 인간 p53AIP1 단백질을 인식하는 토끼 IgG 항체입니다. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 PBS 버퍼에 0.02% sodium azide를 포함합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 4–8 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the amino terminus of human p53AIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152385 |
Product Specific Information
- Suggested positive control: HL60 cell lysate
- PA5-20355 can be used with blocking peptide PEP-0475.
Target Information
The novel protein p53AIP1 (p53-regulated apoptosis-inducing protein 1) has been identified from direct cloning of p53 binding sequences from human genomic DNA. Expression of p53AIP1 in mitochondria is induced by wild-type p53, leading to apoptotic cell death through dissipation of mitochondrial potential.
Severe DNA damage causes phosphorylation of p53 at Ser-46, p53AIP1 expression, and apoptotic cell death. DNA damage-inducible apoptosis is enhanced through transcriptional activation of p53AIP1.
p53R2 is directly regulated by p53 to supply nucleotides for DNA repair, playing a key role in cell survival. Dysfunction of this pathway may activate p53-dependent apoptosis to eliminate damaged cells. Conversely, p53AIP1 mediates p53-dependent apoptosis, and phosphorylation of Ser46 regulates transcriptional activation of this apoptosis-inducing gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific TEP1 Polyclonal Antibody
689,200원
Thermo Fisher Scientific
Thermo Fisher Scientific DARC Polyclonal Antibody
689,200원
Thermo Fisher Scientific
Thermo Fisher Scientific p53AIP1 Polyclonal Antibody
689,200원
Thermo Fisher Scientific
Thermo Fisher Scientific BRSK1 Polyclonal Antibody
689,200원
Thermo Fisher Scientific
Thermo Fisher Scientific PD-1 Polyclonal Antibody
698,000원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|