Thermo Fisher Scientific hnRNP M Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total hnRNP M.

Target Information

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three quasi-RRM domains that bind RNAs and constitutes a monomer of the N-acetylglucosamine-specific receptor, postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.