Thermo Fisher Scientific hnRNP K Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP K Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 hnRNP K 단백질을 검출하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 친화 크로마토그래피로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5115373
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HNRNPK (Accession P61978), corresponding to amino acid residues G260–P310 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900009 |
Product Specific Information
Antibody detects endogenous levels of total HNRNPK.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm. hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and contains three KH domains that bind RNAs. It binds strongly to poly(C) sequences and is thought to play a role in cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-115373_hnRNP_K_P61978-1_Rabbit.svg)
(이미지: PA5-115373_hnRNP_K_P61978-1_Rabbit_PDP.jpeg)
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