
Thermo Fisher Scientific DUSP5 Monoclonal Antibody (2F3)
DUSP5 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, 인간 시료에 반응합니다. Western blot 및 ELISA에 사용 가능하며, 핵 내 ERK1 인산화 조절 연구에 적합합니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F3 |
| Immunogen | DUSP5 (NP_004410, 286 a.a. ~ 384 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
LKEAFDYIKQ RRSMVSPNFG FMGQLLQYES EILPSTPNPQ PPSCQGEAAG SSLIGHLQTL SPDMQGAYCT FPASVLAPVP THSTVSELSR SPVATATSCTarget Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily, which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities, tissue distribution, subcellular localization, and inducibility by extracellular stimuli. DUSP5 inactivates ERK1, is highly expressed in pancreas and brain, and localizes to the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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