Thermo Fisher Scientific DUSP5 Monoclonal Antibody (4C8)
인간 DUSP5 단백질을 인식하는 Mouse monoclonal antibody(클론 4C8). Western blot과 ELISA에 적합하며, 비결합형 액상 형태로 제공. -20°C 보관, 동결/해동 반복 피할 것. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C8 |
| Immunogen | DUSP5 (NP_004410, 286 a.a. ~384 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LKEAFDYIKQ RRSMVSPNFG FMGQLLQYES EILPSTPNPQ PPSCQGEAAG SSLIGHLQTL SPDMQGAYCT FPASVLAPVP THSTVSELSR SPVATATSC
Target Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase (MAPK) superfamily, which are associated with cellular proliferation and differentiation. Different members of this family show distinct substrate specificities, tissue distribution, subcellular localization, and inducibility by extracellular stimuli.
This gene product inactivates ERK1, is expressed in various tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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