Thermo Fisher Scientific RIMS3 Polyclonal Antibody
RIMS3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 고순도 액상 형태로 신경 전달 및 시냅스 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RIMS3 (amino acids 21–120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4), with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rab3-interacting molecules (RIMs) are synaptic proteins essential for neural transmission and plasticity. While RIM1 and RIM2 act as effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known about RIM3. Expression of RIM3 in PC12 cells increases calcium-triggered exocytosis without affecting baseline release, suggesting a role in exocytosis regulation. RIM3 localizes mainly to neuronal dendrites and postsynaptic densities, indicating its contribution to synaptic transmission and plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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