Thermo Fisher Scientific MAP2K1 Monoclonal Antibody (OTI1E5), TrueMAB
MAP2K1 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC/IF에 적합. 다양한 종에 반응하며 고순도 액상 형태로 제공. 연구용으로 세포 성장 및 신호전달 경로 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Full length human recombinant protein of human MAP2K1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation.
MAP2K1 is activated by various growth factors, cytokines, membrane depolarization, and calcium influx.
MEK1 activation occurs via phosphorylation at serine residues 218 and 222 by Raf1.
It participates in stress response signaling, apoptosis, and cytokine-induced proliferation.
Mutations in this gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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