Thermo Fisher Scientific SNAP-23/SNAP-25 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

-

Immunohistochemistry (IHC)

1:300-1:2,000

-

Miscellaneous PubMed (Misc)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from n-terminal region of mouse Synaptosomal-associated protein 23 conjugated to an immunogenic carrier protein was used as the antigen if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SNAP23/SNAP25,uniProtId:O09044-1,ncbiNodeId:10090,antigenRange:1,antigenLength:210,antigenImageFileName:OSS00167W-100UL_SNAP23SNAP25_O09044-1_Rabbit.svg,antigenImageFileNamePDP:OSS00167W-100UL_SNAP23SNAP25_O09044-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The antigen shares 90% identity with SNAP-25.

Specificity of this antibody: SNAP-23 and SNAP-25.

Target Information

SNAP23 is an essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. SNAP25 is involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Subcellular Location: SNAP-23: Cell membrane; Peripheral membrane protein. Cell junction; synapse; synaptosome. Note: Mainly localized to the plasma membrane. SNAP-25: Cytoplasm; perinuclear region. Cell membrane; Lipid-anchor. Cell junction; synapse; synaptosome. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.