Thermo Fisher Scientific OLIG2 Recombinant Rabbit Monoclonal Antibody (SP07-02)
OLIG2 단백질을 인식하는 재조합 토끼 단일클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 높은 특이성과 재현성을 제공합니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SP07-02 |
| Immunogen | Synthetic peptide within Human Olig2 aa 238–287 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809333 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
OLIG2 encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. It regulates ventral neuroectodermal progenitor cell fate and is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia.
The gene is located within chromosome 21, a region implicated in learning deficits associated with Down syndrome.
Tissue specificity: Expressed in the brain, in oligodendrocytes; strongly expressed in oligodendrogliomas; weak to moderate expression in astrocytomas; variable expression in glioblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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