Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (4G7)

Applications

• Western Blot (WB): 1:1,000 dilution tested

Product Specifications

Target Information

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is involved in stress fiber formation and cytokinesis. The protein participates in lamellipodia and filopodia formation in motile cells and may influence neuronal growth-cone guidance. Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.