Thermo Fisher Scientific Collagen II Monoclonal Antibody (6B3)

Applications

Tested Dilution

Publications

Western Blot (WB)

-

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 24 publications 24 publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 6 publications 6 publications

Product Specifications

Species Reactivity

Amphibian, Chicken, Human, Mouse

Published species

Bovine, Human, Lizard, Mouse, Rabbit

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6B3

Immunogen

Purified type II collagen; obtained from the adult chicken sternum by limited pepsinization if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Collagen II,uniProtId:P02460-1,ncbiNodeId:9031,antigenRange:1-859,antigenLength:859,antigenImageFileName:MA5-13026_Collagen_II_P02460-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13026_Collagen_II_P02460-1_House_mouse_PDP.jpeg,sortOrder:5}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10979392

Product Specific Information

MA5-13026 targets Collagen II in IF and IHC (P) applications and shows reactivity with Amphibian, Chicken, Human, and mouse samples.

The MA5-13026 immunogen is purified type II collagen; obtained from the adult chicken sternum by limited pepsinization.

Target Information

COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.