Thermo Fisher Scientific IL22RA1 Polyclonal Antibody
IL22RA1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA 등에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. -20°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human IL-22R (amino acids 41–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
A novel cytokine, designated IL-TIF (IL-10 related T cell-derived inducible factor) and IL-22, was recently identified.
The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a member of the class II cytokine receptor family.
IL-22R forms a complex with the IL-10 receptor beta chain and mediates IL-22 signaling through the JAK-STAT pathway.
IL22R is expressed in normal liver and kidney tissues, as well as in HepG2 and TK-10 cell lines.
A soluble form of IL-22 receptor, termed IL-22 binding protein (IL-22BP, IL-22RA2), prevents IL-22 binding to the cell surface receptor complex and neutralizes IL-22 activity.
LPS induces IL-22 expression, suggesting its role in inflammatory responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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