Thermo Fisher Scientific PDE1A Monoclonal Antibody (OTI5C9), TrueMAB
PDE1A 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, Human 시료에 반응. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로 신호전달 관련 PDE1A 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 259–545 of human PDE1A produced in E.coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide concentrations by hydrolyzing cAMP and/or cGMP to their respective nucleoside 5′-monophosphates.
Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin-dependent enzymes activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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