Thermo Fisher Scientific SIRT2 Recombinant Rabbit Monoclonal Antibody (1E1U3)
SIRT2 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot 및 ELISA에 사용 가능하며, 인간과 랫트 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 제공됩니다.
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Thermo Fisher Scientific SIRT2 Recombinant Rabbit Monoclonal Antibody (1E1U3)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1E1U3 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human SIRT2 (Q8IXJ6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.36 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911982 |
Product Specific Information
Positive test controls include: HeLa, 293T, HepG2.
Immunogen sequence:
MAEPDPSHPL ETQAGKVQEA QDSDSDSEGG AAGGEADMDF LRNLFSQTLS LGSQKERLLD ELTLEGVARY MQSERCRRVI CLVGAGISTS AGIPDFRSPS
Target Information
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) involved in gene silencing, cell cycle regulation, and DNA damage repair.
SIRT2 may act as a tumor suppressor in human gliomas and serve as a molecular marker for these cells. It also functions as a redox sensor regulating muscle gene expression in response to food intake and exercise.
SIRT2 participates in the phosphorylation cascade during mitosis, being phosphorylated in late G2 phase, M phase, and cytokinesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: MA5-42841_SIRT2_Q8IXJ6-1_Rabbit_PDP.jpeg)
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