Thermo Fisher Scientific NSUN2 Recombinant Rabbit Monoclonal Antibody (3H24L11)
NSUN2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 일관된 로트 간 재현성, 높은 특이성과 감도를 제공합니다. 단백질 A 정제, 액상 형태로 제공되며 4°C 단기 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3H24L11 |
| Immunogen | Protein corresponding to Human NSUN2 (aa 350–600) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633051 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, and the best clones are selected for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Gene: NSUN2
Function: Encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). This modification stabilizes anticodon-codon pairing and ensures accurate mRNA translation.
Clinical Relevance: Mutations in NSUN2 are associated with autosomal recessive mental retardation type 5 (MRT5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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