Thermo Fisher Scientific PTF1A Recombinant Rabbit Monoclonal Antibody (12H4L4)

Applications

• Western Blot (WB): 1–2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Bovine, and Rat.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

PTF1A is a component of the pancreas transcription factor 1 complex, playing a crucial role in mammalian pancreatic development. It determines whether cells in pancreatic buds proceed toward pancreatic organogenesis or revert to duodenal fates.
PTF1A maintains exocrine pancreas-specific gene expression, including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis, and loss of expression is observed in ductal-type pancreatic cancers.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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