Thermo Fisher Scientific DCPS Monoclonal Antibody (OTI1E6), TrueMAB
DCPS 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, Lyophilized 형태로 제공. 연구용으로 mRNA 분해 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E6 |
| Immunogen | Full length human recombinant protein of human DCPS produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DCPS is necessary for complete degradation of mRNAs in both normal turnover and nonsense-mediated decay.
It removes the 7-methyl guanine cap structure from short mRNA fragments (<10 nucleotides) produced by 3′→5′ exosome-mediated decay, releasing m7GMP.
Can also degrade m7GDP to m7GMP, but shows no activity toward mRNA molecules longer than 25 nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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