Thermo Fisher Scientific TPT1 Polyclonal Antibody
Thermo Fisher Scientific의 TPT1 Polyclonal Antibody는 인간 TCTP/TPT1 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합하며, 보존제가 없는 고순도 항체로 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:10,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TCTP/TPT1 protein (Met1–Cys172) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788336 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human TCTP/TPT1.
Target Information
TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium-binding proteins. It is localized in the cytoplasm and widely expressed, functioning as a transcriptional activator, calcium transporter, histamine inducer, and anti-apoptotic caspase 3 inhibitor.
TPT1 acts as a cytokine-like molecule that triggers the release of histamine, IL-4, and IL-13 from basophils, as well as IL-8 secretion and calcium response in eosinophils.
It plays a pivotal role in allergic diseases and, due to its broad distribution in the brain, is implicated in neurodegenerative disorders such as Alzheimer’s disease and Down syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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