Thermo Fisher Scientific SRSF11 Polyclonal Antibody
SRSF11 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 고순도(>95%)로 정제되었습니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 260–305 of human SRSF11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553885 |
Product Specific Information
- Detects endogenous SRSF11 protein at approximately 54 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Pre-mRNA splicing enhancer elements are short RNA sequences that activate weak splice sites in nearby introns, essential for accurate splice site recognition and regulation of alternative splicing. These elements bind to serine/arginine (SR)-rich splicing factors such as SC35, 9G8, SRp20, and SF2/ASF.
SR factors contain one or more RNA recognition motifs (RRM) and an SR-rich domain, playing key roles in both constitutive and alternative splicing.
SFRS11 (splicing factor, arginine/serine-rich 11), also known as p54 or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and may function in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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