Thermo Fisher Scientific mGluR4 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human mGluR4 (GRM4). Validated for WB, IHC, and ICC/IF. Affinity purified and supplied in liquid form with 0.5 mg/mL concentration. Suitable for research use in neuroscience and receptor signaling studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to Human GRM4 (amino acids 33–46) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA and 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633274 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in relevant research applications.
It is intended for Research Use Only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Pig, Rabbit, and Cat.
Target Information
The Metabotropic Glutamate Receptor mGluR4 (GRM4) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system. It activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is essential for normal brain function and is implicated in various neuropathologic conditions.
Metabotropic glutamate receptors are a family of G protein-coupled receptors divided into three groups based on sequence homology, signal transduction mechanisms, and pharmacologic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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